Laura Peterson
Lecturer
Phone: 352-294-1364
Email: ude.lfu.mehc|snimajneb#ude.lfu.mehc|snimajneb ude.lfu.mehc|nosretep.arual#ude.lfu.mehc|nosretep.arual
Address University of Florida Department of Chemistry PO Box
117200 Gainesville FL 32611
Education:
2007-2012 – Ph.D. Medicinal Chemistry, The University of Kansas
2003-2007 – B.S., Chemistry, University of Colorado at Colorado Springs
Experience
- Jan 2015- present - Adjunct Instructor, University of Florida
- Jun 2012-May 2014 – Postdoctoral Fellow, Cambridge, MA NIH Ruth L. Kirschstein National Research Service Award Fellow in the Barbara Imperiali and Michael B. Yaffe laboratories:
1) Development of fluorescence-based, selective kinase activity probes
2) Application of kinase activity sensors towards the systematic evaluation of kinase activity in the DNA damage response
- Jun 2007- Jun 2012, Graduate Research Assistant, University of Kansas, Medicinal Chemistry in the Brian S. J. Blagg laboratory:
1) Synthesis and biological evaluation of modulators of Hsp90 with potential for the treatment of cancer and neurodegenerative diseases
2) Assay design and development in efforts to characterize novel Hsp90 inhibitors and isoform selective Hsp90 inhibitors
- Jan 2004 – May 2007, Undergraduate Research Assistant, University of Colorado at Colorado Springs, Analytical Chemistry in the David J. Weiss laboratory:
Investigation of a reagentless biosensor coupled with microchip capillary electrophoresis for the determination of phenylalanine in urine
Featured Skills & Endorsements
Medicinal Chemistry, Assay development, Analytical Chemistry, Laboratory, Cancer, NMR
Publications
Chaitanya A. Patwardhan, Abdul Fauq, Laura B. Peterson, Charles Miller, Brian S. J. Blagg and Ahmed Chadli, Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis, publication date Mar 2013 publication description J. Biol. Chem.
Adam S. Duerfeldt, Laura B. Peterson, Jason C. Maynard, Chun Leung Ng, Davide Eletto, Olga Ostrovsky, Heather E. Shinogle, David S. Moore, Yair Argon, Christopher V. Nicchitta, and Brian S. J. Blagg, Development of a Grp94 Inhibitor, publication date 2012 publication description J. Amer. Chem. Soc.
Bhaskar Reddy Kusuma, Liang Zhang, Teather Sundstrom, Laura B. Peterson, Rick T. Dobrowsky, and Brian S. J. Blagg†, Synthesis and Evaluation of Novologues as C-Terminal Hsp90 Inhibitors with Cytoprotective Activity against Sensory Neuron Glucotoxicity, publication date 2012 publication description J. Med. Chem.
Laura B. Peterson, Jeffrey D. Eskew, George A. Vielhauer, and Brian S. J. Blagg, The hERG Channel Is Dependent upon the Hsp90α Isoform for Maturation and Trafficking, publication date 2012 publication description Mol. Pharm.
Robert L. Matts, Anshuman Dixit, Laura B. Peterson, Liang Sun, Sudhakar Voruganti, Palgunan Kalyanaraman, Steve D. Hartson, Gennady M. Verkhivker, and Brian S. J. Blagg, Elucidation of the Hsp90 C-terminal inhibitor binding site, publication date 2011 publication description ACS Chem. Biol.
Jason Davenport, Jacob R. Manjarrez, Laura Peterson, Brian Krumm, Brian S. J. Blagg, and Robert L. Matts, Gambogic Acid, a Natural Product Inhibitor of Hsp90, publication date 2011 publication description J. Nat. Prod.
Bhaskar Reddy Kusuma, Laura B. Peterson, Huiping Zhao, George Vielhauer, Jeffrey Holzbeierlein, and Brian S. J. Blagg, Targeting the heat shock protein 90 dimer with dimeric inhibitors, publication date 2011 publication description J. Med. Chem.
Laura B.Peterson, Brian S.J.Blagg, Click chemistry to probe Hsp90: Synthesis and evaluation of a series of triazole-containing novobiocin analogues, publication date 2010 publication description Bioorg. Med. Chem. Lett.
Laura B.Peterson, Brian S.J.Blagg, To fold or not to fold: modulation and consequences of Hsp90 inhibition, publication date 2009 publication description Future Med. Chem.
Michael W.Amolins, Laura B.Peterson, Brian S.J.Blagg, Synthesis and evaluation of electron-rich curcumin analogues, publication date 2008 publication description Bioorg. Med. Chem.
David J.Weiss, Megan Dorris, Amanda Loh, A. Laura Peterson, Dehydrogenase based reagentless biosensor for monitoring phenylketonuria, publication date 2007 publication description Biosens. Bioelectron.
Honors & Awards
MIKI Meeting in Miniature Graduate Student Co-Chair, Apr 2011, The University of Kansas, Department of Medicinal Chemistry. Responsible for planning and organizing all aspects of the scientific and social meeting that included participants from The University of Kansas, The University of Minnesota, The University of Iowa, and the University of Illinois-Chicago.
ACS Division of Medicinal Chemistry Pre-Doctoral Fellowship, Sep 2010, ACS Division of Medicinal Chemistry
NIH Dynamic Aspects of Chemical Biology Training Grant Trainee, Jun 2008 National Institutes of Health (T31)
Smissman Fellowship, Aug 2007 honor issuer The University of Kansas Department of Medicinal Chemistry
Chemistry B.S. Graduate of the Year, May 2007, The University of Colorado at Colorado Springs